PEGylated PLGA nanoparticles for the improved delivery of doxorubicin
نویسندگان
چکیده
منابع مشابه
PEGylated PLGA nanoparticles for the improved delivery of doxorubicin.
UNLABELLED We hypothesize that the efficacy of doxorubicin (DOX) can be maximized and dose-limiting cardiotoxicity minimized by controlled release from PEGylated nanoparticles. To test this hypothesis, a unique surface modification technique was used to create PEGylated poly(lactic-co-glycolic acid) (PLGA) nanoparticles encapsulating DOX. An avidin-biotin coupling system was used to control pol...
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ژورنال
عنوان ژورنال: Nanomedicine: Nanotechnology, Biology and Medicine
سال: 2009
ISSN: 1549-9634
DOI: 10.1016/j.nano.2009.02.002